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Reishi Benefits: What Does Research Say?

| Leestijd 5 Minuten

Looking for the source of eternal youth? Well, you’ve found it! In this article, we delve into Reishi and its health benefits, covering relevant scientific research and providing you with everything you want to know about this powerful medicinal mushroom.

Also read: Turkey Tail Benefits: 10 Surprising Health Perks

What are Reishi mushrooms?

Reishi benefits

Reishi, or Ganoderma lucidum, is also known as the mushroom of immortality or eternal youth. It is one of the most famous medicinal mushrooms in both the Eastern and Western worlds.

In traditional Chinese medicine, Reishi mushrooms symbolise a long, happy life. That is why it is also called the king of medicinal mushrooms. In Chinese, that boils down to ‘Ling Zhi.’

What is Reishi used for?

Reishi mushrooms are used to increase energy, strengthen immunity, and fight diseases, including cancer. Scientific studies show interesting results, but more research is needed to support those findings.

People also use Reishi to lower cholesterol and treat urinary problems (frequent urination at night, unexpected urine loss, etc.). At MushPeak, you can get Reishi supplements in the form of organic capsules.

5 health benefits of Reishi

reishi supplements benefits

Do you enjoy being active and want to improve your sports performance or endurance? If so, Reishi supplements can be a good addition to your diet. In fact, Reishi has an enormous number of health benefits, the five most important of which are outlined below.

1. Contribution to stronger immunity

One of the greatest health benefits of Reishi mushrooms is their potential contribution to stronger immunity. Some studies show that Reishi can positively influence genes in white blood cells (1). White blood cells protect your body from infections caused by pathogens, such as bacteria, viruses, fungi, and parasites.

Other studies show that Reishi mushrooms can increase white blood cell counts in people with colon cancer (2).

2. Possible contribution of Reishi to fighting cancer

This scientific review describes how recent studies appear to show a positive effect of Reishi on gastrointestinal cancer (3). Reishi’s ganoderic acids, in particular, seem to have a strong effect on gastrointestinal cancer, particularly in reversing multi-drug resistance (MDR).

3. Reishi Mushrooms against stress, anxiety, and depression

According to some studies, Reishi mushroom can help reduce stress and may even have an effect on depression. Of course, much more research is needed to support these results.

However, this scientific review suggests that some medicinal mushrooms contain compounds (including polysaccharides in Reishi and cordycepin in Cordyceps) that have been shown to affect stress-resistance strategies in laboratory animals (4).

Also, those compounds affect neurobiological mechanisms, including inflammatory responses, HPA function, and neurogenesis, which may be associated with the effects of diet on mild depressive disorders.

4. Possible increased energy with Reishi supplements

Reishi mushrooms can also, according to some studies, increase energy and reduce fatigue.

This double-blind study shows that the placebo group experienced a 20.1% decrease in fatigue after eight weeks. The treatment group experienced a higher decrease of 28.3% (after eight weeks of taking a polysaccharide extract of G. lucidum) (5).

Also read: Cordyceps Benefits: Research + 10 Health Benefits

5. Anti-inflammatory properties of Reishi

One of the most powerful benefits of Reishi mushrooms is their anti-inflammatory properties. According to various studies, the compounds in Reishi appear to reduce inflammation in the body (6).

Inflammation is a major cause of many physical and mental illnesses, including arthritis, intestinal problems, cancer, diabetes, heart disease, and Alzheimer’s disease. By reducing inflammation in the body, Reishi may be able to help prevent these diseases.

What nutrients do Reishi mushrooms contain?

What nutrients in Reishi may be responsible for its health benefits? Let’s explore some of them:

  • Polysaccharides: Reishi contains complex carbohydrates known as polysaccharides, including beta-glucans. These compounds can stimulate the immune system by increasing the activity of white blood cells, particularly macrophages and natural killer (NK) cells.
  • Triterpenes: Reishi also contains triterpenes, such as ganoderic acids. These compounds possess anti-inflammatory properties and can reduce inflammatory responses in the body.
  • Polypeptides: Reishi mushrooms contain proteins and peptides that can enhance the immune response to infections.
  • Antioxidants: Reishi is rich in antioxidants, including vitamin C and selenium, which can help reduce oxidative stress in the body. Excessive oxidative stress can adversely affect the immune system.
  • Adenosine: Reishi contains adenosine, a nucleoside that can regulate the immune system and reduce inflammation.

What are the side effects of Reishi supplements?

Reishi is generally safe, but some people may experience mild stomach upset or lower blood pressure when taking Reishi supplements. Additionally, Reishi can interact with certain medications.

If you’re unsure whether your medications combine well with Reishi, always consult with your doctor before taking Reishi supplements.

How to buy the right mushroom supplements?

buying mushroom supplements tips

Buy your mushroom supplements exclusively from reputable brands that adhere to strict quality control standards. Why? Because mushrooms absorb substances from their environment, which can include harmful elements.

At MushPeak, our mushrooms are cultivated under meticulously controlled conditions and are naturally organic. Each batch of our mushroom supplements undergoes comprehensive testing for safety, efficacy, and quality.

Also read: Buying Functional Mushrooms: Find Your Match

Choose premium Reishi supplements

For optimal Reishi benefits, it’s crucial to choose top-quality products. That’s why MushPeak exclusively offers premium mushroom supplements with no additives—purely organic.

Discover our mushrooms!



Supplements should not be used as a replacement for a diverse diet, a healthy lifestyle, or as a treatment for any medical condition. Keep this product out of the reach of children. If you are ill, pregnant, or in doubt, always consult with your healthcare provider. The information provided on this website is intended for general informational purposes and should not be considered as medical advice. While traditional Chinese medicine has a history spanning thousands of years and has been tested on numerous individuals, MushPeak does not make claims indicating the proven medicinal properties of herbs or mushrooms, in accordance with current EU legislation. Detailed information about mushrooms is available from publicly accessible sources on the Internet. Please feel free to contact us with any questions.


  1. Cheng C. H., Leung A. Y., & Chen C. F. (2010). The effects of two different ganoderma species (Lingzhi) on gene expression in human monocytic THP-1 cells. Nutrition and cancer, 62(5), 648–658.
  2. Chen X., Hu Z. P., Yang X., et al. (2006). Monitoring of immune responses to a herbal immuno-modulator in patients with advanced colorectal cancer. International immunopharmacology, 6(3), 499–508.
  3. Ye T., Ge Y., Jiang X., et al. (2023). A review of anti-tumour effects of Ganoderma lucidum in gastrointestinal cancer. Chinese Medicine, 18, 107.
  4. Fijałkowska A, Jędrejko K, Sułkowska-Ziaja K, Ziaja M, Kała K, Muszyńska B. (2022). Edible Mushrooms as a Potential Component of Dietary Interventions for Major Depressive Disorder. Foods, 11(10), 1489.
  5. Wenbo T., Yihuai G., Guoliang C., et al. (2005). A Randomized, Double-Blind and Placebo-Controlled Study of a Ganoderma lucidum Polysaccharide Extract in Neurasthenia. Journal of Medicinal Food, 8(1), 53-58.
  6. Cör Andrejč D., Knez Ž., & Knez Marevci M. (2022). Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview. Front. Pharmacol, 13:934982.

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